NAICS 325413 - In-Vitro Diagnosic Substance Manufacturing

GENERAL STATISTICS
Year	Companies	Establishments		Employment			Compensation		Production ($ million)
		Total	with 20 or more employees	Total (000)	Production		Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
		Total	with 20 or more employees	Total (000)	Workers (000)	Hours (Mil)	Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
Sources: 1997 and 2002 Economic Census; other years, up to 2006, are from Annual Survey of Manufactures. Establishment counts for non-Census years are from County Business Patterns; 1997 and 2002 values are from the 1997 and 2002 censuses, respectively. ‘P’s show projections by the editors.
1997	202	226	132	36.5	13.4	26.2	1,928.7	21.82	2,207.2	5,955.6	8,145.9	706.7
1998		224	126	40.8	14.2	27.9	2,292.5	21.54	2,460.1	6,287.5	8,912.9	623.4
1999		223	118	40.6	14.9	29.2	2,352.1	21.96	2,656.1	7,044.3	9,567.5	707.0
2000		216	115	40.2	15.4	30.8	2,364.7	22.92	3,019.2	7,366.8	10,351.3	661.3
2001		210	113	41.0	15.7	30.4	2,494.9	24.75	3,216.9	7,895.6	11,026.5	770.4
2002	196	236	132	26.8	10.2	18.5	1,509.1	24.52	1,835.7	5,415.7	7,296.1	277.5
2003		227	131	28.8	10.7	21.5	1,844.3	26.45	2,278.8	6,480.3	8,765.5	256.2
2004		233	133	27.0	9.5	19.3	1,800.5	25.40	2,454.4	6,930.3	9,259.2	247.0
2005		236	133	26.5	9.3	17.9	1,878.5	27.07	3,016.3	7,669.2	10,710.6	275.6
2006		234P	132P	25.6	8.9	17.5	1,876.4	27.81	3,428.3	8,197.6	11,614.7	296.8
2007		235P	133P	22.9P	8.2P	16.0P	1,745.0P	28.43P	3,155.6P	7,545.5P	10,690.8P	144.5P
2008		237P	134P	21.0P	7.4P	14.6P	1,692.5P	29.16P	3,216.0P	7,690.0P	10,895.5P	83.1P
2009		238P	135P	19.1P	6.7P	13.1P	1,639.9P	29.89P	3,276.4P	7,834.5P	11,100.2P	21.6P
2010		240P	136P	17.2P	6.0P	11.7P	1,587.3P	30.62P	3,336.9P	7,978.9P	11,304.9P

INDICES OF CHANGE
Year	Companies	Establishments		Employment			Compensation		Production ($ million)
		Total	with 20 or more employees	Total (000)	Production		Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
		Total	with 20 or more employees	Total (000)	Workers (000)	Hours (Mil)	Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
Sources: Same as General Statistics. Values reflect change from the base year, 2002. Values above 100 mean greater than 2002, values below 100 mean less than 2002, and the values of 100 in other years means the same as 2002. ‘P’s show projections by the editors.
1997	103	96	100	136	131	142	128	89	120	110	112	255
1998		95	95	152	139	151	152	88	134	116	122	225
1999		94	89	151	146	158	156	90	145	130	131	255
2000		92	87	150	151	166	157	93	164	136	142	238
2001		89	86	153	154	164	165	101	175	146	151	278
2002	100	100	100	100	100	100	100	100	100	100	100	100
2003		96	99	107	105	116	122	108	124	120	120	92
2004		99	101	101	93	104	119	104	134	128	127	89
2005		100	101	99	91	97	124	110	164	142	147	99
2006		99P	100P	96	87	95	124	113	187	151	159	107
2007		100P	101P	85P	80P	86P	116P	116P	172P	139P	147P	52P
2008		100P	101P	78P	73P	79P	112P	119P	175P	142P	149P	30P
2009		101P	102P	71P	66P	71P	109P	122P	178P	145P	152P	8P
2010		102P	103P	64P	59P	63P	105P	125P	182P	147P	155P

SELECTED RATIOS
For 2002	Avg. of All Manufact.	Analyzed Industry	Index	For 2002	Avg. of All Manufact.	Analyzed Industry	Index
Sources: Same as General Statistics. The ‘Average of All Manufacturing’ column represents the average of l manufacturing industries reported for the most recent complete year available. The Index shows he relationship between the Average and the Analyzed Industry. For example, 100 means that they are equal; 500 that the Analyzed Industry is five times the average; 50 means that the Analyzed Industry is half the national average. The abbreviation ‘na’ is used to show that data are ‘not available’. Ratios shown for 2002, the last complete census year.
Employees per Establishment	42	114	271	Value Added per Production Worker	182,367	530,951	291
Payroll per Establishment	1,639,184	6,394,492	390	Cost per Establishment	5,769,015	7,778,390	135
Payroll per Employee	39,053	56,310	144	Cost per Employee	137,446	68,496	50
Production Workers per Establishment	30	43	146	Cost per Production Worker	195,506	179,971	92
Wages per Establishment	694,845	1,922,119	277	Shipments per Establishment	11,158,348	30,915,678	277
Wages per Production Worker	23,548	44,473	189	Shipments per Employee	265,847	272,243	102
Hours per Production Worker	1,980	1,814	92	Shipments per Production Worker	378,144	715,304	189
Wages per Hour	11.89	24.52	206	Investment per Establishment	361,338	1,175,847	325
Value Added per Establishment	5,381,325	22,947,881	426	Investment per Employee	8,609	10,354	120
Value Added per Employee	128,210	202,078	158	Investment per Production Worker	12,245	27,206	222

LEADING COMPANIES Number shown: 75 Total sales ($ mil): 14,355 Total employment (000): 52.8
Company Name	Address				CEO Name	Phone	Co. Type	Sales ($ mil)	Empl. (000)
Source: Ward's Business Directory of U.S. Private and Public Companies, Volumes 1 and 2, 2008. The company type code used is as follows: P - Public, R - Private, S - Subsidiary, D - Division, J - Joint Venture, A - Affiliate, G - Group. Sales are in millions of dollars, employees are in thousands. An asterisk (*) indicates an estimated sales volume. The symbol < stands for ‘less than’. Company names and addresses are truncated, in some cases, to fit into the available space.
Church and Dwight Company Inc.	469 N Harrison St.	Princeton	NJ	08543	James R. Craigie	609-683-5900	P	2,221	3.7
Merial Ltd.	3239 Satellite Blvd	Duluth	GA	30096	Gerald Belle	678-638-3000	J	1,900*	5.0
Bio-Rad Laboratories Inc.	1000 Alfrd Nobel Dr	Hercules	CA	94547	Norman Schwartz	510-724-7000	P	1,461	6.4
Charles River Labs Int’l	251 Ballardvale St.	Wilmington	MA	01887	James C. Foster	978-658-6000	P	1,231	8.5
IDEXX Laboratories Inc.	1 Idexx Dr.	Westbrook	ME	04092	Jonathan W. Ayers	207-856-0300	P	923	4.7
Foster City Holdings L.L.C.	850 Lincoln Ctre Dr	Foster City	CA	94404	Michael Hunkapiller	650-638-5800	S	614*	2.3
Inverness Medical Innovations	51 Sawyer Rd.	Waltham	MA	02453		781-647-3900	P	570	2.6
Instrumentation Laboratory Co.	101 Hartwell Ave.	Lexington	MA	02421	Jose Manent	781-861-0710	S	500*	0.6
Diagnostic Products Corp.	5210 Pac Concourse	Los Angeles	CA	90045	Sidney A. Aroesty	310-645-8200	S	481	2.6
Quest Diagnostics Inc.	33608 Ortega Hwy.	S J Capistrano	CA	92675		949-728-4000	S	419*	1.5
Genencor International Inc.	925 Page Mill Rd.	Palo Alto	CA	94304	Robert Mayer	650-846-7500	S	410	1.3
OSI Pharmaceuticals Inc.	41 Pinelawn Rd.	Melville	NY	11747	Colin Goddard	631-962-2000	P	341	0.5
Biosite Inc.	9975 Summers Rdg	San Diego	CA	92121	Kim D. Blickenstaff	858-805-4808	P	309	1.0
Welch Allyn Holdings Inc.	PO Box 220	Skaneateles Fls	NY	13153		315-685-4100	R	227*	1.4
Immucor Inc.	PO Box 5625	Norcross	GA	30091	Gioacchino DeChirico	770-441-2051	P	224	0.6
Prometheus Laboratories Inc.	9410 Carroll Prk Dr	San Diego	CA	92121	Joseph M. Limber	858-824-0895	R	187	0.3
Myriad Genetics Inc.	320 Wakara Way.	Salt Lake City	UT	84108		801-584-3600	P	157	0.8
Digene Corp.	1201 Clopper Rd.	Gaithersburg	MD	20878	Daryl Faulkner	301-944-7000	P	153	0.5
E-Z-EM Inc.	1111 Marcus Ave.	Lake Success	NY	11042	A A. Lombardo	516-333-8230	P	138	0.6
Meridian Bioscience Inc.	3471 River Hills Dr	Cincinnati	OH	45244		513-271-3700	P	123	0.4
Quidel Corp.	10165 McKellar Ct.	San Diego	CA	92121	Caren L. Mason	858-552-1100	P	118	0.3
Scantibodies Laboratory Inc.	9336 Abraham Way	Santee	CA	92071	Thomas Cantor	619-258-9300	R	102*	0.2
Neogen Corp.	620 Lesher Pl.	Lansing	MI	48912	James L. Herbert	517-372-9200	P	86	0.4
OraSure Technologies Inc.	220 E 1st Street	Bethlehem	PA	18015	Michael Gausling	610-882-1820	P	83	0.3
Syntron Bioresearch Inc.	2774 Loker Ave. W	Carlsbad	CA	92008	Jin Lee	760-930-2200	R	82*	0.1
Bionostics Inc.	7 Jackson Rd.	Ayer	MA	01432	Bruce Blessington	978-772-7070	R	67*	0.1
Orchid Cellmark Inc.	4390 U.S. Rte. 1	Princeton	NJ	08540	Thomas Bologna	609-750-2200	P	60	0.4
Ista Pharmaceuticals Inc.	15295 Alton Pky.	Irvine	CA	92618	Vicente Anido	949-788-6000	P	59	0.2
Lexicon Pharmaceuticals Inc.	8800 Tech. Forest	The Woodlands	TX	77381		281-863-3000	P	50	0.6
Fujirebio Diagnostics Inc.	201 Great Vly Pky.	Malvern	PA	19355	Takeo Hayashi	610-240-3800	S	46*	0.1
Streck Inc.	7002 S 109th St.	La Vista	NE	68128	Jeanne Buland	402-333-1982	R	45*	0.3
BioSource International Inc.	542 Flynn Rd.	Camarillo	CA	93012	Gregory Lucier	805-987-0086	S	44	0.2
Monogram Biosciences Inc.	345 Oyster Point	S San Francisco	CA	94080		650-635-1100	P	43	0.3
Human Genome Sciences Inc.	14200 Shady Grove	Rockville	MD	20850		301-309-8504	P	42	0.9
CIS-US Inc.	10 Deangelo Dr.	Bedford	MA	01730	Glenn Alto	781-275-7120	R	38*	<0.1
Oscient Pharmaceuticals Corp.	1000 Winter St.	Waltham	MA	02451		781-398-2300	P	38	0.3
Ess Group Inc.	78 Carranza Rd.	Vincentown	NJ	08088	James Egan	609-268-1200	R	38*	<0.1
Neogen Corp.- Animal Safety	944 Nandino Blvd.	Lexington	KY	40511	James Huebert	859-254-1221	S	34*	0.1
MEDTOX Diagnostics Inc.	1238 Anthony Rd.	Burlington	NC	27215	Richard Braun	336-226-6311	S	33*	<0.1
Teco Diagnostics Inc.	1268 N Lakeview	Anaheim	CA	92807	K Chen	714-693-7788	R	29*	<0.1
Worthington Bio Chemical Corp.	730 Vassar Ave.	Lakewood	NJ	08701	Von Worthington	732-942-1660	R	29*	<0.1
Athena Diagnostics Inc.	Four Biotech Park	Worcester	MA	01605	Robert E. Flaherty	508-756-2886	R	27*	0.1
Diagnostic Hybrids Inc.	1055 East State St.	Athens	OH	45701	David Scholl	740-589-3300	R	27*	0.1
Bioserv Corp.	5340 Eastgate Mall	San Diego	CA	92121	Jeanne Dunham	858-450-3123	R	26*	<0.1
International Immunology Corp.	25549 Adams Ave.	Murrieta	CA	92562	Shunsaku Shibota	951-677-5629	R	25*	<0.1
Raven Biological Laboratories	PO Box 27261	Omaha	NE	68127	Robert Dwyer	402-593-0781	R	25*	<0.1
BioVeris Corp.	16020 Industrial Dr	Gaithersburg	MD	20877		301-869-9800	P	24	0.2
Promega Biosciences Inc.	277 Granada Dr.	San Luis Obispo	CA	93401	Kristen Yetter	805-544-8524	R	24*	<0.1
Am. Biological Technologies	940 Crossroads Blvd	Seguin	TX	78155	Michael Schrage	830-372-1391	R	23*	<0.1
Biolog Inc.	21124 Cabot Blvd.	Hayward	CA	94545	Barry Bochner	510-785-2564	R	23*	<0.1
INOVA Diagnostics Inc.	10180 Scripps Ranch	San Diego	CA	92131		858-586-9900	R	22*	<0.1
Biogenex Laboratories	4600 Norris Cyn Rd.	San Ramon	CA	94583	Kris Kalra	925-275-0550	R	21*	0.1
Cytogen Corp.	650 College Rd. E	Princeton	NJ	08540	Michael D. Becker	609-750-8200	P	20	<0.1
Sonus Pharmaceuticals Inc.	22026 20th Ave. SE	Bothell	WA	98021	Michael A. Martino	425-487-9500	P	20	<0.1
Hycor Biomedical Inc.	7272 Chapman Ave.	Garden Grove	CA	92841	Joseph Sorge	714-933-3000	S	20*	0.1
Genetic Testing Institute Inc.	20925 Crossroads	Waukesha	WI	53186	Jim Tidey	262-754-1000	R	19*	<0.1
MML Diagnostics Packaging Inc.	PO Box 458	Troutdale	OR	97060	Dale Pestes	503-666-8398	R	19*	<0.1
Diagnostic Systems Labs	PO Box 57946	Webster	TX	77598	Gopal Savjani	281-332-9678	R	19*	0.1
Antigen Laboratories Inc.	PO Box 123	Liberty	MO	64069	Tom Willoughby	816-781-5222	R	18*	<0.1
Bion Enterprises Ltd.	455 State St., 100	Des Plaines	IL	60016	Edward Nowakowski	847-544-5044	R	16*	<0.1
Midland Bioproducts Corp.	PO Box 309	Boone	IA	50036	Richard Jorgenson	515-432-5516	R	15*	<0.1
Quantimetrix Corp.	2005 Mnhattan Bch	Redondo Beach	CA	90278	Robert W. Ban	310-536-0006	R	15*	<0.1
Antibodies Inc.	PO Box 1560	Davis	CA	95617	Richard Krogsrud	530-758-4400	R	15*	<0.1
Palatin Technologies Inc.	4-C Cedar Brook Dr.	Cranbury	NJ	08512	John K.A. Prendergast	609-495-2200	P	14	<0.1
GTC Biotherapeutics Inc.	175 Crossing Blvd.	Framingham	MA	01702	Geoffrey F. Cox	508-620-9700	P	14	0.2
Alpha Innotech Corp.	2401 Merced St.	San Leandro	CA	94577	Ron Bissinger	510-483-9620	P	13	<0.1
Matritech Inc.	330 Nevada St.	Newton	MA	02460	Stephen D. Chubb	617-928-0820	P	12	<0.1
GBF Inc.	PO Box 16123	Greensboro	NC	27416	Danny Bowman	336-665-0205	R	12*	<0.1
Valley Biomedical Prods/Svcs	121 Industrial Dr.	Winchester	VA	22602	Mario Romano	540-868-0800	R	12*	<0.1
EnviroLogix Inc.	500 Riverside Inds.	Portland	ME	04103	Bruce Ferguson	207-797-0300	R	12*	<0.1
CHEMetrics Inc.	4295 Catlett Rd.	Calverton	VA	20138	Gordon Rampy	540-788-9026	R	11*	<0.1
Vicam L.P.	313 Pleasant St.	Watertown	MA	02472	Jack Radlo	617-926-7045	R	10*	<0.1
Regis Technologies Inc.	8210 Austin Ave.	Morton Grove	IL	60053	Louis Glunz	847-967-6000	R	10*	<0.1
Immunomedics Inc.	300 American Rd.	Morris Plains	NJ	07950	David M. Goldenberg	973-605-8200	P	9	0.1
Peninsula Laboratories Inc.	305 Old County Rd.	San Carlos	CA	94070	Damier Vidovich	650-592-5392	R	9*	<0.1

MATERIALS CONSUMED
Material	Quantity	Delivered Cost ($ million)
Source: 2002 Economic Census. Explanation of symbols used: (D): Withheld to avoid disclosure of competitive data; na: Not available; (S): Withheld because statistical norms were not met; (X): Not applicable; (Z): Less than half the unit shown; nec: Not elsewhere classified; nsk: Not specified by kind; - : zero; p : 10–19 percent estimated; q : 20–29 percent estimated.
Antibiotics (bulk), for human and veterinary use	(X)	9.5
Agricultural products, crude (incl. flowers, grains, seeds, herbs, etc.)	(X)	0.4
Processed food and kindred products (lactose, meat packing plant products, yeast, etc.)	(X)	(D)
Blood derivatives and extenders	(X)	43.8
All other bulk medicinal and botanical uncompounded drugs	(X)	83.3
Gelatin (pharmaceutical grade) and gelatin capsules	(X)	(D)
Alcohols, excluding ethyl (100 percent basis)	(X)	2.5
Cyclic crudes and intermediates (including organic colors)	(X)	(D)
Other synthetic organic chemicals	(X)	33.1
Fabricated plastics products (excluding containers)	(X)	64.6
Metal closures and crowns for containers	(X)	1.4
Labels, coupons, instructions, and other printed material	(X)	41.1
Plastics containers	(X)	24.6
Glass containers	(X)	32.5
Metal containers	(X)	(D)
Paperboard containers, boxes, and corrugated paperboard	(X)	41.5
All other materials, components, parts, containers, and supplies	(X)	1,085.3
Materials, ingredients, containers, and supplies, nsk	(X)	107.3

PRODUCT SHARE DETAILS
Product or Product Class Shipments	$ Mil.	Product or Product Class Shipments	$ Mil.
Source: 2002 Economic Census. The values are product shipments in millions of dollars for 2002. Total product shipments may be lower or higher than industry shipments. See Introduction for a full discussion. Values of indented subcategories are summed in the main heading(s). The symbol (D) appears when data are withheld to prevent disclosure of competitive information. The abbreviation nsk stands for ‘not specified by kind’ and nec for ‘not elsewhere classified’. A dash (-) means zero.
DIAGNOSTIC SUBSTANCES, IN VITRO	7,962.4	Diagnostic substances, in vitro diagnostic hematology products	77.4
Diagnostic substances, in vitro diagnostic (clinical chemistry) reagents, including toxicology	5,707.8	Diagnostic substances, in vitro diagnostic coagulation products	121.3
Diagnostic substances, in vitro diagnostic (clinical chemistry) standards and controls, including toxicology	672.8	Diagnostic substances, in vitro diagnostic microbiology, virology, serology, cytology, and histology products	337.0
Diagnostic substances, in vitro diagnostic blood bank, hematology, and coagulation products	488.9	Diagnostic substances, in vitro, culture media	40.4
Diagnostic substances, in vitro diagnostic blood bank products	290.2	Diagnostic substances, in vitro, other	513.8
		Diagnostic substances, in vitro, nsk, total	201.7

INPUTS AND OUTPUTS FOR IN-VITRO DIAGNOSTIC SUBSTANCE MANUFACTURING
Economic Sector or Industry Providing Inputs	%	Sector	Economic Sector or Industry Buying Outputs	%	Sector
Compensation of employees	25.6		Hospitals	68.2	Services
Management of companies & enterprises	20.1	Services	Physician, dentist, other health practitioner offices	21.2	Services
Scientific research & development services	7.1	Services	Medical & diagnostic labs & outpatient services	3.7	Services
Pharmaceutical preparations	6.2	Manufg.	Pharmaceutical preparations	2.1	Manufg.
Biological products (except diagnostic)	6.1	Manufg.	In-vitro diagnostic substances	1.3	Manufg.
Wholesale trade	4.0	Trade	Colleges, universities, & professional schools	0.9	Services
Lessors of nonfinancial assets	3.4	Fin/R.E.	Individual & family services	0.5	Services
In-vitro diagnostic substances	1.7	Manufg.	Exports of goods & services	0.3	Cap Inv
Management, scientific, & technical consulting	1.5	Services	Medicinal & botanical manufacturing	0.3	Manufg.
Medicinal & botanical manufacturing	1.1	Manufg.	Nursing & residential care facilities	0.3	Services
Real estate	1.0	Fin/R.E.	Change in private inventories	0.3	In House
Advertising & related services	1.0	Services	Maintenance/repair of nonresidential structures	0.3	Construct.
Power generation & supply	0.9	Util.	Biological products (except diagnostic)	0.2	Manufg.
Professional, scientific, technical services, nec	0.9	Services	Architectural, engineering, & related services	0.1	Services
Monetary authorities/depository credit intermediation	0.8	Fin/R.E.
Plastics products, nec	0.7	Manufg.
Legal services	0.6	Services
Paperboard containers	0.5	Manufg.
Printing	0.5	Manufg.
Telecommunications	0.5	Services
Basic organic chemicals, nec	0.5	Manufg.
Truck transportation	0.4	Util.
Business support services	0.3	Services
Accounting, tax preparation, bookkeeping, & payroll	0.3	Services
Warehousing & storage	0.3	Util.
Taxes on production & imports, less subsidies	0.3
Food services & drinking places	0.3	Services
Glass containers	0.3	Manufg.
Data processing, hosting, & related services	0.3	Services

INPUTS AND OUTPUTS FOR IN-VITRO DIAGNOSTIC SUBSTANCE MANUFACTURING - Continued
Economic Sector or Industry Providing Inputs	%	Sector	Economic Sector or Industry Buying Outputs	%	Sector
Source: Benchmark Input-Output Accounts for the U.S. Economy, 2002, U.S. Department of Commerce, Washington, D.C., January 2008. The abbreviation nec stands for ‘not elsewhere classified’.
Architectural, engineering, & related services	0.2	Services
Automotive equipment rental & leasing	0.2	Fin/R.E.
Services to buildings & dwellings	0.2	Services
Employment services	0.2	Services
Maintenance/repair of nonresidential structures	0.2	Construct.
Environmental & other technical consulting services	0.2	Services
Other computer related services, including facilities	0.2	Services
Office administrative services	0.2	Services
Plastics bottles	0.2	Manufg.
Petroleum refineries	0.2	Manufg.
Plastics packaging materials, film & sheet	0.2	Manufg.
Animal, except poultry, processing	0.2	Manufg.
Fabricated metals, nec	0.1	Manufg.
Chemical products & preparations, nec	0.1	Manufg.
Securities, commodity contracts, investments	0.1	Fin/R.E.
Industrial gases	0.1	Manufg.
Automotive repair & maintenance, ex. car washes	0.1	Services
Pressed & blown glass & glassware, nec	0.1	Manufg.
Commercial & industrial machinery rental & leasing	0.1	Fin/R.E.
Nondepository credit intermediation activities	0.1	Fin/R.E.
Hotels & motels, including casino hotels	0.1	Services

OCCUPATIONS EMPLOYED BY PHARMACEUTICAL & MEDICINE MANUFACTURING
Occupation	% of Total 2006	Change to 2016	Occupation	% of Total 2006	Change to 2016
Source: Industry-Occupation Matrix, Bureau of Labor Statistics, December 4, 2007. These data are reported based on 4-digit NAICS categories but have been matched to corresponding 6-digit NAICS industry codes. The change reported for each occupation to the year 2016 is a percent of growth or decline as estimated by the Bureau of Labor Statistics. The abbreviation nec stands for ‘not elsewhere classified’.
Packaging & filling machine operators & tenders	7.0	13.4	General & operations managers	1.6	13.4
Chemists	5.2	13.4	Biochemists & biophysicists	1.4	26.0
Mixing & blending machine operators & tenders	3.6	26.0	Machine feeders & offbearers	1.4	13.4
Chemical equipment operators & tenders	3.5	26.0	Packers & packagers, hand	1.4	0.8
Medical scientists, exc epidemiologists	3.4	26.0	Shipping, receiving, & traffic clerks	1.4	21.3
Inspectors, testers, sorters, samplers, & weighers	3.0	18.8	Customer service representatives	1.4	38.6
First-line supervisors/managers of production workers	2.6	26.0	Secretaries, exc legal, medical, & executive	1.3	12.1
Biological technicians	2.5	26.0	Industrial production managers	1.3	26.0
Chemical technicians	2.3	26.0	Managers, nec	1.3	26.0
Maintenance & repair workers, general	2.1	26.0	Production workers, nec	1.2	23.7
Sales representatives, wholesale & manufacturing, tech	2.0	26.0	Office clerks, general	1.2	24.2
Separating, precipitating, & still machine operators	1.9	26.0	Microbiologists	1.1	26.0
Business operation specialists, nec	1.8	38.6	Industrial machinery mechanics	1.1	44.9
Executive secretaries & administrative assistants	1.7	26.0	Accountants & auditors	1.1	26.0
Team assemblers	1.7	26.0	Natural sciences managers	1.1	26.0
Laborers & freight, stock, & material movers, hand	1.6	13.4	Production, planning, & expediting clerks	1.1	26.0

INDUSTRY DATA BY STATE
State	Establishments	Shipments			Employment				Cost as % of Shipments	Investment per Employee($)
State	Establishments	Total ($ mil)	% of U.S.	Per Establ.	Total Number	% of U.S.	Per Establ.	Wages ($/hour)	Cost as % of Shipments	Investment per Employee($)
Source: 2002 Economic Census. The states are in descending order of shipments or establishments (if shipment data are missing for the majority). The symbol (D) appears when data are withheld to prevent disclosure of competitive information. States marked with (D) are sorted by number of establishments. A dash (-) indicates that the data element cannot be calculated. Data may not show all states active in the NAICS category. All data available at the time of publication are shown.
California	67	1,595.6	21.9	23,815.1	7,701	28.7	115	22.01	22.7	14,297
New York	9	573.6	7.9	63,733.3	1,774	6.6	197	24.00	19.9	13,541
Massachusetts	11	459.3	6.3	41,753.0	1,976	7.4	180	16.03	16.0	10,503
Texas	13	137.9	1.9	10,604.0	553	2.1	43	27.00	41.5	4,479
Minnesota	6	125.1	1.7	20,851.0	292	1.1	49	24.75	36.7	10,747
Maine	7	124.4	1.7	17,767.0	1,294	4.8	185	24.54	25.4	5,389
Florida	5	99.7	1.4	19,946.6	449	1.7	90	22.73	30.1	10,085
Wisconsin	7	45.1	0.6	6,445.4	231	0.9	33	16.43	23.5	4,545

NAICS 325413 - In-Vitro Diagnosic Substance Manufacturing

GENERAL STATISTICS
Year	Companies	Establishments		Employment			Compensation		Production ($ million)
		Total	with 20 or more employees	Total (000)	Production		Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
		Total	with 20 or more employees	Total (000)	Workers (000)	Hours (Mil)	Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
Sources: 1997 and 2002 Economic Census; other years, up to 2006, are from Annual Survey of Manufactures. Establishment counts for non-Census years are from County Business Patterns; 1997 and 2002 values are from the 1997 and 2002 censuses, respectively. ‘P’s show projections by the editors.
1997	202	226	132	36.5	13.4	26.2	1,928.7	21.82	2,207.2	5,955.6	8,145.9	706.7
1998		224	126	40.8	14.2	27.9	2,292.5	21.54	2,460.1	6,287.5	8,912.9	623.4
1999		223	118	40.6	14.9	29.2	2,352.1	21.96	2,656.1	7,044.3	9,567.5	707.0
2000		216	115	40.2	15.4	30.8	2,364.7	22.92	3,019.2	7,366.8	10,351.3	661.3
2001		210	113	41.0	15.7	30.4	2,494.9	24.75	3,216.9	7,895.6	11,026.5	770.4
2002	196	236	132	26.8	10.2	18.5	1,509.1	24.52	1,835.7	5,415.7	7,296.1	277.5
2003		227	131	28.8	10.7	21.5	1,844.3	26.45	2,278.8	6,480.3	8,765.5	256.2
2004		233	133	27.0	9.5	19.3	1,800.5	25.40	2,454.4	6,930.3	9,259.2	247.0
2005		236	133	26.5	9.3	17.9	1,878.5	27.07	3,016.3	7,669.2	10,710.6	275.6
2006		234P	132P	25.6	8.9	17.5	1,876.4	27.81	3,428.3	8,197.6	11,614.7	296.8
2007		235P	133P	22.9P	8.2P	16.0P	1,745.0P	28.43P	3,155.6P	7,545.5P	10,690.8P	144.5P
2008		237P	134P	21.0P	7.4P	14.6P	1,692.5P	29.16P	3,216.0P	7,690.0P	10,895.5P	83.1P
2009		238P	135P	19.1P	6.7P	13.1P	1,639.9P	29.89P	3,276.4P	7,834.5P	11,100.2P	21.6P
2010		240P	136P	17.2P	6.0P	11.7P	1,587.3P	30.62P	3,336.9P	7,978.9P	11,304.9P

INDICES OF CHANGE
Year	Companies	Establishments		Employment			Compensation		Production ($ million)
		Total	with 20 or more employees	Total (000)	Production		Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
		Total	with 20 or more employees	Total (000)	Workers (000)	Hours (Mil)	Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
Sources: Same as General Statistics. Values reflect change from the base year, 2002. Values above 100 mean greater than 2002, values below 100 mean less than 2002, and the values of 100 in other years means the same as 2002. ‘P’s show projections by the editors.
1997	103	96	100	136	131	142	128	89	120	110	112	255
1998		95	95	152	139	151	152	88	134	116	122	225
1999		94	89	151	146	158	156	90	145	130	131	255
2000		92	87	150	151	166	157	93	164	136	142	238
2001		89	86	153	154	164	165	101	175	146	151	278
2002	100	100	100	100	100	100	100	100	100	100	100	100
2003		96	99	107	105	116	122	108	124	120	120	92
2004		99	101	101	93	104	119	104	134	128	127	89
2005		100	101	99	91	97	124	110	164	142	147	99
2006		99P	100P	96	87	95	124	113	187	151	159	107
2007		100P	101P	85P	80P	86P	116P	116P	172P	139P	147P	52P
2008		100P	101P	78P	73P	79P	112P	119P	175P	142P	149P	30P
2009		101P	102P	71P	66P	71P	109P	122P	178P	145P	152P	8P
2010		102P	103P	64P	59P	63P	105P	125P	182P	147P	155P

SELECTED RATIOS
For 2002	Avg. of All Manufact.	Analyzed Industry	Index	For 2002	Avg. of All Manufact.	Analyzed Industry	Index
Sources: Same as General Statistics. The ‘Average of All Manufacturing’ column represents the average of l manufacturing industries reported for the most recent complete year available. The Index shows he relationship between the Average and the Analyzed Industry. For example, 100 means that they are equal; 500 that the Analyzed Industry is five times the average; 50 means that the Analyzed Industry is half the national average. The abbreviation ‘na’ is used to show that data are ‘not available’. Ratios shown for 2002, the last complete census year.
Employees per Establishment	42	114	271	Value Added per Production Worker	182,367	530,951	291
Payroll per Establishment	1,639,184	6,394,492	390	Cost per Establishment	5,769,015	7,778,390	135
Payroll per Employee	39,053	56,310	144	Cost per Employee	137,446	68,496	50
Production Workers per Establishment	30	43	146	Cost per Production Worker	195,506	179,971	92
Wages per Establishment	694,845	1,922,119	277	Shipments per Establishment	11,158,348	30,915,678	277
Wages per Production Worker	23,548	44,473	189	Shipments per Employee	265,847	272,243	102
Hours per Production Worker	1,980	1,814	92	Shipments per Production Worker	378,144	715,304	189
Wages per Hour	11.89	24.52	206	Investment per Establishment	361,338	1,175,847	325
Value Added per Establishment	5,381,325	22,947,881	426	Investment per Employee	8,609	10,354	120
Value Added per Employee	128,210	202,078	158	Investment per Production Worker	12,245	27,206	222

LEADING COMPANIES Number shown: 75 Total sales ($ mil): 14,355 Total employment (000): 52.8
Company Name	Address				CEO Name	Phone	Co. Type	Sales ($ mil)	Empl. (000)
Source: Ward's Business Directory of U.S. Private and Public Companies, Volumes 1 and 2, 2008. The company type code used is as follows: P - Public, R - Private, S - Subsidiary, D - Division, J - Joint Venture, A - Affiliate, G - Group. Sales are in millions of dollars, employees are in thousands. An asterisk (*) indicates an estimated sales volume. The symbol < stands for ‘less than’. Company names and addresses are truncated, in some cases, to fit into the available space.
Church and Dwight Company Inc.	469 N Harrison St.	Princeton	NJ	08543	James R. Craigie	609-683-5900	P	2,221	3.7
Merial Ltd.	3239 Satellite Blvd	Duluth	GA	30096	Gerald Belle	678-638-3000	J	1,900*	5.0
Bio-Rad Laboratories Inc.	1000 Alfrd Nobel Dr	Hercules	CA	94547	Norman Schwartz	510-724-7000	P	1,461	6.4
Charles River Labs Int’l	251 Ballardvale St.	Wilmington	MA	01887	James C. Foster	978-658-6000	P	1,231	8.5
IDEXX Laboratories Inc.	1 Idexx Dr.	Westbrook	ME	04092	Jonathan W. Ayers	207-856-0300	P	923	4.7
Foster City Holdings L.L.C.	850 Lincoln Ctre Dr	Foster City	CA	94404	Michael Hunkapiller	650-638-5800	S	614*	2.3
Inverness Medical Innovations	51 Sawyer Rd.	Waltham	MA	02453		781-647-3900	P	570	2.6
Instrumentation Laboratory Co.	101 Hartwell Ave.	Lexington	MA	02421	Jose Manent	781-861-0710	S	500*	0.6
Diagnostic Products Corp.	5210 Pac Concourse	Los Angeles	CA	90045	Sidney A. Aroesty	310-645-8200	S	481	2.6
Quest Diagnostics Inc.	33608 Ortega Hwy.	S J Capistrano	CA	92675		949-728-4000	S	419*	1.5
Genencor International Inc.	925 Page Mill Rd.	Palo Alto	CA	94304	Robert Mayer	650-846-7500	S	410	1.3
OSI Pharmaceuticals Inc.	41 Pinelawn Rd.	Melville	NY	11747	Colin Goddard	631-962-2000	P	341	0.5
Biosite Inc.	9975 Summers Rdg	San Diego	CA	92121	Kim D. Blickenstaff	858-805-4808	P	309	1.0
Welch Allyn Holdings Inc.	PO Box 220	Skaneateles Fls	NY	13153		315-685-4100	R	227*	1.4
Immucor Inc.	PO Box 5625	Norcross	GA	30091	Gioacchino DeChirico	770-441-2051	P	224	0.6
Prometheus Laboratories Inc.	9410 Carroll Prk Dr	San Diego	CA	92121	Joseph M. Limber	858-824-0895	R	187	0.3
Myriad Genetics Inc.	320 Wakara Way.	Salt Lake City	UT	84108		801-584-3600	P	157	0.8
Digene Corp.	1201 Clopper Rd.	Gaithersburg	MD	20878	Daryl Faulkner	301-944-7000	P	153	0.5
E-Z-EM Inc.	1111 Marcus Ave.	Lake Success	NY	11042	A A. Lombardo	516-333-8230	P	138	0.6
Meridian Bioscience Inc.	3471 River Hills Dr	Cincinnati	OH	45244		513-271-3700	P	123	0.4
Quidel Corp.	10165 McKellar Ct.	San Diego	CA	92121	Caren L. Mason	858-552-1100	P	118	0.3
Scantibodies Laboratory Inc.	9336 Abraham Way	Santee	CA	92071	Thomas Cantor	619-258-9300	R	102*	0.2
Neogen Corp.	620 Lesher Pl.	Lansing	MI	48912	James L. Herbert	517-372-9200	P	86	0.4
OraSure Technologies Inc.	220 E 1st Street	Bethlehem	PA	18015	Michael Gausling	610-882-1820	P	83	0.3
Syntron Bioresearch Inc.	2774 Loker Ave. W	Carlsbad	CA	92008	Jin Lee	760-930-2200	R	82*	0.1
Bionostics Inc.	7 Jackson Rd.	Ayer	MA	01432	Bruce Blessington	978-772-7070	R	67*	0.1
Orchid Cellmark Inc.	4390 U.S. Rte. 1	Princeton	NJ	08540	Thomas Bologna	609-750-2200	P	60	0.4
Ista Pharmaceuticals Inc.	15295 Alton Pky.	Irvine	CA	92618	Vicente Anido	949-788-6000	P	59	0.2
Lexicon Pharmaceuticals Inc.	8800 Tech. Forest	The Woodlands	TX	77381		281-863-3000	P	50	0.6
Fujirebio Diagnostics Inc.	201 Great Vly Pky.	Malvern	PA	19355	Takeo Hayashi	610-240-3800	S	46*	0.1
Streck Inc.	7002 S 109th St.	La Vista	NE	68128	Jeanne Buland	402-333-1982	R	45*	0.3
BioSource International Inc.	542 Flynn Rd.	Camarillo	CA	93012	Gregory Lucier	805-987-0086	S	44	0.2
Monogram Biosciences Inc.	345 Oyster Point	S San Francisco	CA	94080		650-635-1100	P	43	0.3
Human Genome Sciences Inc.	14200 Shady Grove	Rockville	MD	20850		301-309-8504	P	42	0.9
CIS-US Inc.	10 Deangelo Dr.	Bedford	MA	01730	Glenn Alto	781-275-7120	R	38*	<0.1
Oscient Pharmaceuticals Corp.	1000 Winter St.	Waltham	MA	02451		781-398-2300	P	38	0.3
Ess Group Inc.	78 Carranza Rd.	Vincentown	NJ	08088	James Egan	609-268-1200	R	38*	<0.1
Neogen Corp.- Animal Safety	944 Nandino Blvd.	Lexington	KY	40511	James Huebert	859-254-1221	S	34*	0.1
MEDTOX Diagnostics Inc.	1238 Anthony Rd.	Burlington	NC	27215	Richard Braun	336-226-6311	S	33*	<0.1
Teco Diagnostics Inc.	1268 N Lakeview	Anaheim	CA	92807	K Chen	714-693-7788	R	29*	<0.1
Worthington Bio Chemical Corp.	730 Vassar Ave.	Lakewood	NJ	08701	Von Worthington	732-942-1660	R	29*	<0.1
Athena Diagnostics Inc.	Four Biotech Park	Worcester	MA	01605	Robert E. Flaherty	508-756-2886	R	27*	0.1
Diagnostic Hybrids Inc.	1055 East State St.	Athens	OH	45701	David Scholl	740-589-3300	R	27*	0.1
Bioserv Corp.	5340 Eastgate Mall	San Diego	CA	92121	Jeanne Dunham	858-450-3123	R	26*	<0.1
International Immunology Corp.	25549 Adams Ave.	Murrieta	CA	92562	Shunsaku Shibota	951-677-5629	R	25*	<0.1
Raven Biological Laboratories	PO Box 27261	Omaha	NE	68127	Robert Dwyer	402-593-0781	R	25*	<0.1
BioVeris Corp.	16020 Industrial Dr	Gaithersburg	MD	20877		301-869-9800	P	24	0.2
Promega Biosciences Inc.	277 Granada Dr.	San Luis Obispo	CA	93401	Kristen Yetter	805-544-8524	R	24*	<0.1
Am. Biological Technologies	940 Crossroads Blvd	Seguin	TX	78155	Michael Schrage	830-372-1391	R	23*	<0.1
Biolog Inc.	21124 Cabot Blvd.	Hayward	CA	94545	Barry Bochner	510-785-2564	R	23*	<0.1
INOVA Diagnostics Inc.	10180 Scripps Ranch	San Diego	CA	92131		858-586-9900	R	22*	<0.1
Biogenex Laboratories	4600 Norris Cyn Rd.	San Ramon	CA	94583	Kris Kalra	925-275-0550	R	21*	0.1
Cytogen Corp.	650 College Rd. E	Princeton	NJ	08540	Michael D. Becker	609-750-8200	P	20	<0.1
Sonus Pharmaceuticals Inc.	22026 20th Ave. SE	Bothell	WA	98021	Michael A. Martino	425-487-9500	P	20	<0.1
Hycor Biomedical Inc.	7272 Chapman Ave.	Garden Grove	CA	92841	Joseph Sorge	714-933-3000	S	20*	0.1
Genetic Testing Institute Inc.	20925 Crossroads	Waukesha	WI	53186	Jim Tidey	262-754-1000	R	19*	<0.1
MML Diagnostics Packaging Inc.	PO Box 458	Troutdale	OR	97060	Dale Pestes	503-666-8398	R	19*	<0.1
Diagnostic Systems Labs	PO Box 57946	Webster	TX	77598	Gopal Savjani	281-332-9678	R	19*	0.1
Antigen Laboratories Inc.	PO Box 123	Liberty	MO	64069	Tom Willoughby	816-781-5222	R	18*	<0.1
Bion Enterprises Ltd.	455 State St., 100	Des Plaines	IL	60016	Edward Nowakowski	847-544-5044	R	16*	<0.1
Midland Bioproducts Corp.	PO Box 309	Boone	IA	50036	Richard Jorgenson	515-432-5516	R	15*	<0.1
Quantimetrix Corp.	2005 Mnhattan Bch	Redondo Beach	CA	90278	Robert W. Ban	310-536-0006	R	15*	<0.1
Antibodies Inc.	PO Box 1560	Davis	CA	95617	Richard Krogsrud	530-758-4400	R	15*	<0.1
Palatin Technologies Inc.	4-C Cedar Brook Dr.	Cranbury	NJ	08512	John K.A. Prendergast	609-495-2200	P	14	<0.1
GTC Biotherapeutics Inc.	175 Crossing Blvd.	Framingham	MA	01702	Geoffrey F. Cox	508-620-9700	P	14	0.2
Alpha Innotech Corp.	2401 Merced St.	San Leandro	CA	94577	Ron Bissinger	510-483-9620	P	13	<0.1
Matritech Inc.	330 Nevada St.	Newton	MA	02460	Stephen D. Chubb	617-928-0820	P	12	<0.1
GBF Inc.	PO Box 16123	Greensboro	NC	27416	Danny Bowman	336-665-0205	R	12*	<0.1
Valley Biomedical Prods/Svcs	121 Industrial Dr.	Winchester	VA	22602	Mario Romano	540-868-0800	R	12*	<0.1
EnviroLogix Inc.	500 Riverside Inds.	Portland	ME	04103	Bruce Ferguson	207-797-0300	R	12*	<0.1
CHEMetrics Inc.	4295 Catlett Rd.	Calverton	VA	20138	Gordon Rampy	540-788-9026	R	11*	<0.1
Vicam L.P.	313 Pleasant St.	Watertown	MA	02472	Jack Radlo	617-926-7045	R	10*	<0.1
Regis Technologies Inc.	8210 Austin Ave.	Morton Grove	IL	60053	Louis Glunz	847-967-6000	R	10*	<0.1
Immunomedics Inc.	300 American Rd.	Morris Plains	NJ	07950	David M. Goldenberg	973-605-8200	P	9	0.1
Peninsula Laboratories Inc.	305 Old County Rd.	San Carlos	CA	94070	Damier Vidovich	650-592-5392	R	9*	<0.1

MATERIALS CONSUMED
Material	Quantity	Delivered Cost ($ million)
Source: 2002 Economic Census. Explanation of symbols used: (D): Withheld to avoid disclosure of competitive data; na: Not available; (S): Withheld because statistical norms were not met; (X): Not applicable; (Z): Less than half the unit shown; nec: Not elsewhere classified; nsk: Not specified by kind; - : zero; p : 10–19 percent estimated; q : 20–29 percent estimated.
Antibiotics (bulk), for human and veterinary use	(X)	9.5
Agricultural products, crude (incl. flowers, grains, seeds, herbs, etc.)	(X)	0.4
Processed food and kindred products (lactose, meat packing plant products, yeast, etc.)	(X)	(D)
Blood derivatives and extenders	(X)	43.8
All other bulk medicinal and botanical uncompounded drugs	(X)	83.3
Gelatin (pharmaceutical grade) and gelatin capsules	(X)	(D)
Alcohols, excluding ethyl (100 percent basis)	(X)	2.5
Cyclic crudes and intermediates (including organic colors)	(X)	(D)
Other synthetic organic chemicals	(X)	33.1
Fabricated plastics products (excluding containers)	(X)	64.6
Metal closures and crowns for containers	(X)	1.4
Labels, coupons, instructions, and other printed material	(X)	41.1
Plastics containers	(X)	24.6
Glass containers	(X)	32.5
Metal containers	(X)	(D)
Paperboard containers, boxes, and corrugated paperboard	(X)	41.5
All other materials, components, parts, containers, and supplies	(X)	1,085.3
Materials, ingredients, containers, and supplies, nsk	(X)	107.3

PRODUCT SHARE DETAILS
Product or Product Class Shipments	$ Mil.	Product or Product Class Shipments	$ Mil.
Source: 2002 Economic Census. The values are product shipments in millions of dollars for 2002. Total product shipments may be lower or higher than industry shipments. See Introduction for a full discussion. Values of indented subcategories are summed in the main heading(s). The symbol (D) appears when data are withheld to prevent disclosure of competitive information. The abbreviation nsk stands for ‘not specified by kind’ and nec for ‘not elsewhere classified’. A dash (-) means zero.
DIAGNOSTIC SUBSTANCES, IN VITRO	7,962.4	Diagnostic substances, in vitro diagnostic hematology products	77.4
Diagnostic substances, in vitro diagnostic (clinical chemistry) reagents, including toxicology	5,707.8	Diagnostic substances, in vitro diagnostic coagulation products	121.3
Diagnostic substances, in vitro diagnostic (clinical chemistry) standards and controls, including toxicology	672.8	Diagnostic substances, in vitro diagnostic microbiology, virology, serology, cytology, and histology products	337.0
Diagnostic substances, in vitro diagnostic blood bank, hematology, and coagulation products	488.9	Diagnostic substances, in vitro, culture media	40.4
Diagnostic substances, in vitro diagnostic blood bank products	290.2	Diagnostic substances, in vitro, other	513.8
		Diagnostic substances, in vitro, nsk, total	201.7

INPUTS AND OUTPUTS FOR IN-VITRO DIAGNOSTIC SUBSTANCE MANUFACTURING
Economic Sector or Industry Providing Inputs	%	Sector	Economic Sector or Industry Buying Outputs	%	Sector
Compensation of employees	25.6		Hospitals	68.2	Services
Management of companies & enterprises	20.1	Services	Physician, dentist, other health practitioner offices	21.2	Services
Scientific research & development services	7.1	Services	Medical & diagnostic labs & outpatient services	3.7	Services
Pharmaceutical preparations	6.2	Manufg.	Pharmaceutical preparations	2.1	Manufg.
Biological products (except diagnostic)	6.1	Manufg.	In-vitro diagnostic substances	1.3	Manufg.
Wholesale trade	4.0	Trade	Colleges, universities, & professional schools	0.9	Services
Lessors of nonfinancial assets	3.4	Fin/R.E.	Individual & family services	0.5	Services
In-vitro diagnostic substances	1.7	Manufg.	Exports of goods & services	0.3	Cap Inv
Management, scientific, & technical consulting	1.5	Services	Medicinal & botanical manufacturing	0.3	Manufg.
Medicinal & botanical manufacturing	1.1	Manufg.	Nursing & residential care facilities	0.3	Services
Real estate	1.0	Fin/R.E.	Change in private inventories	0.3	In House
Advertising & related services	1.0	Services	Maintenance/repair of nonresidential structures	0.3	Construct.
Power generation & supply	0.9	Util.	Biological products (except diagnostic)	0.2	Manufg.
Professional, scientific, technical services, nec	0.9	Services	Architectural, engineering, & related services	0.1	Services
Monetary authorities/depository credit intermediation	0.8	Fin/R.E.
Plastics products, nec	0.7	Manufg.
Legal services	0.6	Services
Paperboard containers	0.5	Manufg.
Printing	0.5	Manufg.
Telecommunications	0.5	Services
Basic organic chemicals, nec	0.5	Manufg.
Truck transportation	0.4	Util.
Business support services	0.3	Services
Accounting, tax preparation, bookkeeping, & payroll	0.3	Services
Warehousing & storage	0.3	Util.
Taxes on production & imports, less subsidies	0.3
Food services & drinking places	0.3	Services
Glass containers	0.3	Manufg.
Data processing, hosting, & related services	0.3	Services

INPUTS AND OUTPUTS FOR IN-VITRO DIAGNOSTIC SUBSTANCE MANUFACTURING - Continued
Economic Sector or Industry Providing Inputs	%	Sector	Economic Sector or Industry Buying Outputs	%	Sector
Source: Benchmark Input-Output Accounts for the U.S. Economy, 2002, U.S. Department of Commerce, Washington, D.C., January 2008. The abbreviation nec stands for ‘not elsewhere classified’.
Architectural, engineering, & related services	0.2	Services
Automotive equipment rental & leasing	0.2	Fin/R.E.
Services to buildings & dwellings	0.2	Services
Employment services	0.2	Services
Maintenance/repair of nonresidential structures	0.2	Construct.
Environmental & other technical consulting services	0.2	Services
Other computer related services, including facilities	0.2	Services
Office administrative services	0.2	Services
Plastics bottles	0.2	Manufg.
Petroleum refineries	0.2	Manufg.
Plastics packaging materials, film & sheet	0.2	Manufg.
Animal, except poultry, processing	0.2	Manufg.
Fabricated metals, nec	0.1	Manufg.
Chemical products & preparations, nec	0.1	Manufg.
Securities, commodity contracts, investments	0.1	Fin/R.E.
Industrial gases	0.1	Manufg.
Automotive repair & maintenance, ex. car washes	0.1	Services
Pressed & blown glass & glassware, nec	0.1	Manufg.
Commercial & industrial machinery rental & leasing	0.1	Fin/R.E.
Nondepository credit intermediation activities	0.1	Fin/R.E.
Hotels & motels, including casino hotels	0.1	Services

OCCUPATIONS EMPLOYED BY PHARMACEUTICAL & MEDICINE MANUFACTURING
Occupation	% of Total 2006	Change to 2016	Occupation	% of Total 2006	Change to 2016
Source: Industry-Occupation Matrix, Bureau of Labor Statistics, December 4, 2007. These data are reported based on 4-digit NAICS categories but have been matched to corresponding 6-digit NAICS industry codes. The change reported for each occupation to the year 2016 is a percent of growth or decline as estimated by the Bureau of Labor Statistics. The abbreviation nec stands for ‘not elsewhere classified’.
Packaging & filling machine operators & tenders	7.0	13.4	General & operations managers	1.6	13.4
Chemists	5.2	13.4	Biochemists & biophysicists	1.4	26.0
Mixing & blending machine operators & tenders	3.6	26.0	Machine feeders & offbearers	1.4	13.4
Chemical equipment operators & tenders	3.5	26.0	Packers & packagers, hand	1.4	0.8
Medical scientists, exc epidemiologists	3.4	26.0	Shipping, receiving, & traffic clerks	1.4	21.3
Inspectors, testers, sorters, samplers, & weighers	3.0	18.8	Customer service representatives	1.4	38.6
First-line supervisors/managers of production workers	2.6	26.0	Secretaries, exc legal, medical, & executive	1.3	12.1
Biological technicians	2.5	26.0	Industrial production managers	1.3	26.0
Chemical technicians	2.3	26.0	Managers, nec	1.3	26.0
Maintenance & repair workers, general	2.1	26.0	Production workers, nec	1.2	23.7
Sales representatives, wholesale & manufacturing, tech	2.0	26.0	Office clerks, general	1.2	24.2
Separating, precipitating, & still machine operators	1.9	26.0	Microbiologists	1.1	26.0
Business operation specialists, nec	1.8	38.6	Industrial machinery mechanics	1.1	44.9
Executive secretaries & administrative assistants	1.7	26.0	Accountants & auditors	1.1	26.0
Team assemblers	1.7	26.0	Natural sciences managers	1.1	26.0
Laborers & freight, stock, & material movers, hand	1.6	13.4	Production, planning, & expediting clerks	1.1	26.0

INDUSTRY DATA BY STATE
State	Establishments	Shipments			Employment				Cost as % of Shipments	Investment per Employee($)
State	Establishments	Total ($ mil)	% of U.S.	Per Establ.	Total Number	% of U.S.	Per Establ.	Wages ($/hour)	Cost as % of Shipments	Investment per Employee($)
Source: 2002 Economic Census. The states are in descending order of shipments or establishments (if shipment data are missing for the majority). The symbol (D) appears when data are withheld to prevent disclosure of competitive information. States marked with (D) are sorted by number of establishments. A dash (-) indicates that the data element cannot be calculated. Data may not show all states active in the NAICS category. All data available at the time of publication are shown.
California	67	1,595.6	21.9	23,815.1	7,701	28.7	115	22.01	22.7	14,297
New York	9	573.6	7.9	63,733.3	1,774	6.6	197	24.00	19.9	13,541
Massachusetts	11	459.3	6.3	41,753.0	1,976	7.4	180	16.03	16.0	10,503
Texas	13	137.9	1.9	10,604.0	553	2.1	43	27.00	41.5	4,479
Minnesota	6	125.1	1.7	20,851.0	292	1.1	49	24.75	36.7	10,747
Maine	7	124.4	1.7	17,767.0	1,294	4.8	185	24.54	25.4	5,389
Florida	5	99.7	1.4	19,946.6	449	1.7	90	22.73	30.1	10,085
Wisconsin	7	45.1	0.6	6,445.4	231	0.9	33	16.43	23.5	4,545

NAICS 325413 - In-Vitro Diagnosic Substance Manufacturing

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NAICS 325413 - In-Vitro Diagnosic Substance Manufacturing

GENERAL STATISTICS
Year	Companies	Establishments		Employment			Compensation		Production ($ million)
		Total	with 20 or more employees	Total (000)	Production		Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
		Total	with 20 or more employees	Total (000)	Workers (000)	Hours (Mil)	Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
Sources: 1997 and 2002 Economic Census; other years, up to 2006, are from Annual Survey of Manufactures. Establishment counts for non-Census years are from County Business Patterns; 1997 and 2002 values are from the 1997 and 2002 censuses, respectively. ‘P’s show projections by the editors.
1997	202	226	132	36.5	13.4	26.2	1,928.7	21.82	2,207.2	5,955.6	8,145.9	706.7
1998		224	126	40.8	14.2	27.9	2,292.5	21.54	2,460.1	6,287.5	8,912.9	623.4
1999		223	118	40.6	14.9	29.2	2,352.1	21.96	2,656.1	7,044.3	9,567.5	707.0
2000		216	115	40.2	15.4	30.8	2,364.7	22.92	3,019.2	7,366.8	10,351.3	661.3
2001		210	113	41.0	15.7	30.4	2,494.9	24.75	3,216.9	7,895.6	11,026.5	770.4
2002	196	236	132	26.8	10.2	18.5	1,509.1	24.52	1,835.7	5,415.7	7,296.1	277.5
2003		227	131	28.8	10.7	21.5	1,844.3	26.45	2,278.8	6,480.3	8,765.5	256.2
2004		233	133	27.0	9.5	19.3	1,800.5	25.40	2,454.4	6,930.3	9,259.2	247.0
2005		236	133	26.5	9.3	17.9	1,878.5	27.07	3,016.3	7,669.2	10,710.6	275.6
2006		234P	132P	25.6	8.9	17.5	1,876.4	27.81	3,428.3	8,197.6	11,614.7	296.8
2007		235P	133P	22.9P	8.2P	16.0P	1,745.0P	28.43P	3,155.6P	7,545.5P	10,690.8P	144.5P
2008		237P	134P	21.0P	7.4P	14.6P	1,692.5P	29.16P	3,216.0P	7,690.0P	10,895.5P	83.1P
2009		238P	135P	19.1P	6.7P	13.1P	1,639.9P	29.89P	3,276.4P	7,834.5P	11,100.2P	21.6P
2010		240P	136P	17.2P	6.0P	11.7P	1,587.3P	30.62P	3,336.9P	7,978.9P	11,304.9P

INDICES OF CHANGE
Year	Companies	Establishments		Employment			Compensation		Production ($ million)
		Total	with 20 or more employees	Total (000)	Production		Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
		Total	with 20 or more employees	Total (000)	Workers (000)	Hours (Mil)	Payroll ($ mil)	Wages ($/hr)	Cost of Materials	Value Added by Manufacture	Value of Shipments	Capital Invest.
Sources: Same as General Statistics. Values reflect change from the base year, 2002. Values above 100 mean greater than 2002, values below 100 mean less than 2002, and the values of 100 in other years means the same as 2002. ‘P’s show projections by the editors.
1997	103	96	100	136	131	142	128	89	120	110	112	255
1998		95	95	152	139	151	152	88	134	116	122	225
1999		94	89	151	146	158	156	90	145	130	131	255
2000		92	87	150	151	166	157	93	164	136	142	238
2001		89	86	153	154	164	165	101	175	146	151	278
2002	100	100	100	100	100	100	100	100	100	100	100	100
2003		96	99	107	105	116	122	108	124	120	120	92
2004		99	101	101	93	104	119	104	134	128	127	89
2005		100	101	99	91	97	124	110	164	142	147	99
2006		99P	100P	96	87	95	124	113	187	151	159	107
2007		100P	101P	85P	80P	86P	116P	116P	172P	139P	147P	52P
2008		100P	101P	78P	73P	79P	112P	119P	175P	142P	149P	30P
2009		101P	102P	71P	66P	71P	109P	122P	178P	145P	152P	8P
2010		102P	103P	64P	59P	63P	105P	125P	182P	147P	155P

SELECTED RATIOS
For 2002	Avg. of All Manufact.	Analyzed Industry	Index	For 2002	Avg. of All Manufact.	Analyzed Industry	Index
Sources: Same as General Statistics. The ‘Average of All Manufacturing’ column represents the average of l manufacturing industries reported for the most recent complete year available. The Index shows he relationship between the Average and the Analyzed Industry. For example, 100 means that they are equal; 500 that the Analyzed Industry is five times the average; 50 means that the Analyzed Industry is half the national average. The abbreviation ‘na’ is used to show that data are ‘not available’. Ratios shown for 2002, the last complete census year.
Employees per Establishment	42	114	271	Value Added per Production Worker	182,367	530,951	291
Payroll per Establishment	1,639,184	6,394,492	390	Cost per Establishment	5,769,015	7,778,390	135
Payroll per Employee	39,053	56,310	144	Cost per Employee	137,446	68,496	50
Production Workers per Establishment	30	43	146	Cost per Production Worker	195,506	179,971	92
Wages per Establishment	694,845	1,922,119	277	Shipments per Establishment	11,158,348	30,915,678	277
Wages per Production Worker	23,548	44,473	189	Shipments per Employee	265,847	272,243	102
Hours per Production Worker	1,980	1,814	92	Shipments per Production Worker	378,144	715,304	189
Wages per Hour	11.89	24.52	206	Investment per Establishment	361,338	1,175,847	325
Value Added per Establishment	5,381,325	22,947,881	426	Investment per Employee	8,609	10,354	120
Value Added per Employee	128,210	202,078	158	Investment per Production Worker	12,245	27,206	222

LEADING COMPANIES Number shown: 75 Total sales ($ mil): 14,355 Total employment (000): 52.8
Company Name	Address				CEO Name	Phone	Co. Type	Sales ($ mil)	Empl. (000)
Source: Ward's Business Directory of U.S. Private and Public Companies, Volumes 1 and 2, 2008. The company type code used is as follows: P - Public, R - Private, S - Subsidiary, D - Division, J - Joint Venture, A - Affiliate, G - Group. Sales are in millions of dollars, employees are in thousands. An asterisk (*) indicates an estimated sales volume. The symbol < stands for ‘less than’. Company names and addresses are truncated, in some cases, to fit into the available space.
Church and Dwight Company Inc.	469 N Harrison St.	Princeton	NJ	08543	James R. Craigie	609-683-5900	P	2,221	3.7
Merial Ltd.	3239 Satellite Blvd	Duluth	GA	30096	Gerald Belle	678-638-3000	J	1,900*	5.0
Bio-Rad Laboratories Inc.	1000 Alfrd Nobel Dr	Hercules	CA	94547	Norman Schwartz	510-724-7000	P	1,461	6.4
Charles River Labs Int’l	251 Ballardvale St.	Wilmington	MA	01887	James C. Foster	978-658-6000	P	1,231	8.5
IDEXX Laboratories Inc.	1 Idexx Dr.	Westbrook	ME	04092	Jonathan W. Ayers	207-856-0300	P	923	4.7
Foster City Holdings L.L.C.	850 Lincoln Ctre Dr	Foster City	CA	94404	Michael Hunkapiller	650-638-5800	S	614*	2.3
Inverness Medical Innovations	51 Sawyer Rd.	Waltham	MA	02453		781-647-3900	P	570	2.6
Instrumentation Laboratory Co.	101 Hartwell Ave.	Lexington	MA	02421	Jose Manent	781-861-0710	S	500*	0.6
Diagnostic Products Corp.	5210 Pac Concourse	Los Angeles	CA	90045	Sidney A. Aroesty	310-645-8200	S	481	2.6
Quest Diagnostics Inc.	33608 Ortega Hwy.	S J Capistrano	CA	92675		949-728-4000	S	419*	1.5
Genencor International Inc.	925 Page Mill Rd.	Palo Alto	CA	94304	Robert Mayer	650-846-7500	S	410	1.3
OSI Pharmaceuticals Inc.	41 Pinelawn Rd.	Melville	NY	11747	Colin Goddard	631-962-2000	P	341	0.5
Biosite Inc.	9975 Summers Rdg	San Diego	CA	92121	Kim D. Blickenstaff	858-805-4808	P	309	1.0
Welch Allyn Holdings Inc.	PO Box 220	Skaneateles Fls	NY	13153		315-685-4100	R	227*	1.4
Immucor Inc.	PO Box 5625	Norcross	GA	30091	Gioacchino DeChirico	770-441-2051	P	224	0.6
Prometheus Laboratories Inc.	9410 Carroll Prk Dr	San Diego	CA	92121	Joseph M. Limber	858-824-0895	R	187	0.3
Myriad Genetics Inc.	320 Wakara Way.	Salt Lake City	UT	84108		801-584-3600	P	157	0.8
Digene Corp.	1201 Clopper Rd.	Gaithersburg	MD	20878	Daryl Faulkner	301-944-7000	P	153	0.5
E-Z-EM Inc.	1111 Marcus Ave.	Lake Success	NY	11042	A A. Lombardo	516-333-8230	P	138	0.6
Meridian Bioscience Inc.	3471 River Hills Dr	Cincinnati	OH	45244		513-271-3700	P	123	0.4
Quidel Corp.	10165 McKellar Ct.	San Diego	CA	92121	Caren L. Mason	858-552-1100	P	118	0.3
Scantibodies Laboratory Inc.	9336 Abraham Way	Santee	CA	92071	Thomas Cantor	619-258-9300	R	102*	0.2
Neogen Corp.	620 Lesher Pl.	Lansing	MI	48912	James L. Herbert	517-372-9200	P	86	0.4
OraSure Technologies Inc.	220 E 1st Street	Bethlehem	PA	18015	Michael Gausling	610-882-1820	P	83	0.3
Syntron Bioresearch Inc.	2774 Loker Ave. W	Carlsbad	CA	92008	Jin Lee	760-930-2200	R	82*	0.1
Bionostics Inc.	7 Jackson Rd.	Ayer	MA	01432	Bruce Blessington	978-772-7070	R	67*	0.1
Orchid Cellmark Inc.	4390 U.S. Rte. 1	Princeton	NJ	08540	Thomas Bologna	609-750-2200	P	60	0.4
Ista Pharmaceuticals Inc.	15295 Alton Pky.	Irvine	CA	92618	Vicente Anido	949-788-6000	P	59	0.2
Lexicon Pharmaceuticals Inc.	8800 Tech. Forest	The Woodlands	TX	77381		281-863-3000	P	50	0.6
Fujirebio Diagnostics Inc.	201 Great Vly Pky.	Malvern	PA	19355	Takeo Hayashi	610-240-3800	S	46*	0.1
Streck Inc.	7002 S 109th St.	La Vista	NE	68128	Jeanne Buland	402-333-1982	R	45*	0.3
BioSource International Inc.	542 Flynn Rd.	Camarillo	CA	93012	Gregory Lucier	805-987-0086	S	44	0.2
Monogram Biosciences Inc.	345 Oyster Point	S San Francisco	CA	94080		650-635-1100	P	43	0.3
Human Genome Sciences Inc.	14200 Shady Grove	Rockville	MD	20850		301-309-8504	P	42	0.9
CIS-US Inc.	10 Deangelo Dr.	Bedford	MA	01730	Glenn Alto	781-275-7120	R	38*	<0.1
Oscient Pharmaceuticals Corp.	1000 Winter St.	Waltham	MA	02451		781-398-2300	P	38	0.3
Ess Group Inc.	78 Carranza Rd.	Vincentown	NJ	08088	James Egan	609-268-1200	R	38*	<0.1
Neogen Corp.- Animal Safety	944 Nandino Blvd.	Lexington	KY	40511	James Huebert	859-254-1221	S	34*	0.1
MEDTOX Diagnostics Inc.	1238 Anthony Rd.	Burlington	NC	27215	Richard Braun	336-226-6311	S	33*	<0.1
Teco Diagnostics Inc.	1268 N Lakeview	Anaheim	CA	92807	K Chen	714-693-7788	R	29*	<0.1
Worthington Bio Chemical Corp.	730 Vassar Ave.	Lakewood	NJ	08701	Von Worthington	732-942-1660	R	29*	<0.1
Athena Diagnostics Inc.	Four Biotech Park	Worcester	MA	01605	Robert E. Flaherty	508-756-2886	R	27*	0.1
Diagnostic Hybrids Inc.	1055 East State St.	Athens	OH	45701	David Scholl	740-589-3300	R	27*	0.1
Bioserv Corp.	5340 Eastgate Mall	San Diego	CA	92121	Jeanne Dunham	858-450-3123	R	26*	<0.1
International Immunology Corp.	25549 Adams Ave.	Murrieta	CA	92562	Shunsaku Shibota	951-677-5629	R	25*	<0.1
Raven Biological Laboratories	PO Box 27261	Omaha	NE	68127	Robert Dwyer	402-593-0781	R	25*	<0.1
BioVeris Corp.	16020 Industrial Dr	Gaithersburg	MD	20877		301-869-9800	P	24	0.2
Promega Biosciences Inc.	277 Granada Dr.	San Luis Obispo	CA	93401	Kristen Yetter	805-544-8524	R	24*	<0.1
Am. Biological Technologies	940 Crossroads Blvd	Seguin	TX	78155	Michael Schrage	830-372-1391	R	23*	<0.1
Biolog Inc.	21124 Cabot Blvd.	Hayward	CA	94545	Barry Bochner	510-785-2564	R	23*	<0.1
INOVA Diagnostics Inc.	10180 Scripps Ranch	San Diego	CA	92131		858-586-9900	R	22*	<0.1
Biogenex Laboratories	4600 Norris Cyn Rd.	San Ramon	CA	94583	Kris Kalra	925-275-0550	R	21*	0.1
Cytogen Corp.	650 College Rd. E	Princeton	NJ	08540	Michael D. Becker	609-750-8200	P	20	<0.1
Sonus Pharmaceuticals Inc.	22026 20th Ave. SE	Bothell	WA	98021	Michael A. Martino	425-487-9500	P	20	<0.1
Hycor Biomedical Inc.	7272 Chapman Ave.	Garden Grove	CA	92841	Joseph Sorge	714-933-3000	S	20*	0.1
Genetic Testing Institute Inc.	20925 Crossroads	Waukesha	WI	53186	Jim Tidey	262-754-1000	R	19*	<0.1
MML Diagnostics Packaging Inc.	PO Box 458	Troutdale	OR	97060	Dale Pestes	503-666-8398	R	19*	<0.1
Diagnostic Systems Labs	PO Box 57946	Webster	TX	77598	Gopal Savjani	281-332-9678	R	19*	0.1
Antigen Laboratories Inc.	PO Box 123	Liberty	MO	64069	Tom Willoughby	816-781-5222	R	18*	<0.1
Bion Enterprises Ltd.	455 State St., 100	Des Plaines	IL	60016	Edward Nowakowski	847-544-5044	R	16*	<0.1
Midland Bioproducts Corp.	PO Box 309	Boone	IA	50036	Richard Jorgenson	515-432-5516	R	15*	<0.1
Quantimetrix Corp.	2005 Mnhattan Bch	Redondo Beach	CA	90278	Robert W. Ban	310-536-0006	R	15*	<0.1
Antibodies Inc.	PO Box 1560	Davis	CA	95617	Richard Krogsrud	530-758-4400	R	15*	<0.1
Palatin Technologies Inc.	4-C Cedar Brook Dr.	Cranbury	NJ	08512	John K.A. Prendergast	609-495-2200	P	14	<0.1
GTC Biotherapeutics Inc.	175 Crossing Blvd.	Framingham	MA	01702	Geoffrey F. Cox	508-620-9700	P	14	0.2
Alpha Innotech Corp.	2401 Merced St.	San Leandro	CA	94577	Ron Bissinger	510-483-9620	P	13	<0.1
Matritech Inc.	330 Nevada St.	Newton	MA	02460	Stephen D. Chubb	617-928-0820	P	12	<0.1
GBF Inc.	PO Box 16123	Greensboro	NC	27416	Danny Bowman	336-665-0205	R	12*	<0.1
Valley Biomedical Prods/Svcs	121 Industrial Dr.	Winchester	VA	22602	Mario Romano	540-868-0800	R	12*	<0.1
EnviroLogix Inc.	500 Riverside Inds.	Portland	ME	04103	Bruce Ferguson	207-797-0300	R	12*	<0.1
CHEMetrics Inc.	4295 Catlett Rd.	Calverton	VA	20138	Gordon Rampy	540-788-9026	R	11*	<0.1
Vicam L.P.	313 Pleasant St.	Watertown	MA	02472	Jack Radlo	617-926-7045	R	10*	<0.1
Regis Technologies Inc.	8210 Austin Ave.	Morton Grove	IL	60053	Louis Glunz	847-967-6000	R	10*	<0.1
Immunomedics Inc.	300 American Rd.	Morris Plains	NJ	07950	David M. Goldenberg	973-605-8200	P	9	0.1
Peninsula Laboratories Inc.	305 Old County Rd.	San Carlos	CA	94070	Damier Vidovich	650-592-5392	R	9*	<0.1

MATERIALS CONSUMED
Material	Quantity	Delivered Cost ($ million)
Source: 2002 Economic Census. Explanation of symbols used: (D): Withheld to avoid disclosure of competitive data; na: Not available; (S): Withheld because statistical norms were not met; (X): Not applicable; (Z): Less than half the unit shown; nec: Not elsewhere classified; nsk: Not specified by kind; - : zero; p : 10–19 percent estimated; q : 20–29 percent estimated.
Antibiotics (bulk), for human and veterinary use	(X)	9.5
Agricultural products, crude (incl. flowers, grains, seeds, herbs, etc.)	(X)	0.4
Processed food and kindred products (lactose, meat packing plant products, yeast, etc.)	(X)	(D)
Blood derivatives and extenders	(X)	43.8
All other bulk medicinal and botanical uncompounded drugs	(X)	83.3
Gelatin (pharmaceutical grade) and gelatin capsules	(X)	(D)
Alcohols, excluding ethyl (100 percent basis)	(X)	2.5
Cyclic crudes and intermediates (including organic colors)	(X)	(D)
Other synthetic organic chemicals	(X)	33.1
Fabricated plastics products (excluding containers)	(X)	64.6
Metal closures and crowns for containers	(X)	1.4
Labels, coupons, instructions, and other printed material	(X)	41.1
Plastics containers	(X)	24.6
Glass containers	(X)	32.5
Metal containers	(X)	(D)
Paperboard containers, boxes, and corrugated paperboard	(X)	41.5
All other materials, components, parts, containers, and supplies	(X)	1,085.3
Materials, ingredients, containers, and supplies, nsk	(X)	107.3

PRODUCT SHARE DETAILS
Product or Product Class Shipments	$ Mil.	Product or Product Class Shipments	$ Mil.
Source: 2002 Economic Census. The values are product shipments in millions of dollars for 2002. Total product shipments may be lower or higher than industry shipments. See Introduction for a full discussion. Values of indented subcategories are summed in the main heading(s). The symbol (D) appears when data are withheld to prevent disclosure of competitive information. The abbreviation nsk stands for ‘not specified by kind’ and nec for ‘not elsewhere classified’. A dash (-) means zero.
DIAGNOSTIC SUBSTANCES, IN VITRO	7,962.4	Diagnostic substances, in vitro diagnostic hematology products	77.4
Diagnostic substances, in vitro diagnostic (clinical chemistry) reagents, including toxicology	5,707.8	Diagnostic substances, in vitro diagnostic coagulation products	121.3
Diagnostic substances, in vitro diagnostic (clinical chemistry) standards and controls, including toxicology	672.8	Diagnostic substances, in vitro diagnostic microbiology, virology, serology, cytology, and histology products	337.0
Diagnostic substances, in vitro diagnostic blood bank, hematology, and coagulation products	488.9	Diagnostic substances, in vitro, culture media	40.4
Diagnostic substances, in vitro diagnostic blood bank products	290.2	Diagnostic substances, in vitro, other	513.8
		Diagnostic substances, in vitro, nsk, total	201.7

INPUTS AND OUTPUTS FOR IN-VITRO DIAGNOSTIC SUBSTANCE MANUFACTURING
Economic Sector or Industry Providing Inputs	%	Sector	Economic Sector or Industry Buying Outputs	%	Sector
Compensation of employees	25.6		Hospitals	68.2	Services
Management of companies & enterprises	20.1	Services	Physician, dentist, other health practitioner offices	21.2	Services
Scientific research & development services	7.1	Services	Medical & diagnostic labs & outpatient services	3.7	Services
Pharmaceutical preparations	6.2	Manufg.	Pharmaceutical preparations	2.1	Manufg.
Biological products (except diagnostic)	6.1	Manufg.	In-vitro diagnostic substances	1.3	Manufg.
Wholesale trade	4.0	Trade	Colleges, universities, & professional schools	0.9	Services
Lessors of nonfinancial assets	3.4	Fin/R.E.	Individual & family services	0.5	Services
In-vitro diagnostic substances	1.7	Manufg.	Exports of goods & services	0.3	Cap Inv
Management, scientific, & technical consulting	1.5	Services	Medicinal & botanical manufacturing	0.3	Manufg.
Medicinal & botanical manufacturing	1.1	Manufg.	Nursing & residential care facilities	0.3	Services
Real estate	1.0	Fin/R.E.	Change in private inventories	0.3	In House
Advertising & related services	1.0	Services	Maintenance/repair of nonresidential structures	0.3	Construct.
Power generation & supply	0.9	Util.	Biological products (except diagnostic)	0.2	Manufg.
Professional, scientific, technical services, nec	0.9	Services	Architectural, engineering, & related services	0.1	Services
Monetary authorities/depository credit intermediation	0.8	Fin/R.E.
Plastics products, nec	0.7	Manufg.
Legal services	0.6	Services
Paperboard containers	0.5	Manufg.
Printing	0.5	Manufg.
Telecommunications	0.5	Services
Basic organic chemicals, nec	0.5	Manufg.
Truck transportation	0.4	Util.
Business support services	0.3	Services
Accounting, tax preparation, bookkeeping, & payroll	0.3	Services
Warehousing & storage	0.3	Util.
Taxes on production & imports, less subsidies	0.3
Food services & drinking places	0.3	Services
Glass containers	0.3	Manufg.
Data processing, hosting, & related services	0.3	Services

INPUTS AND OUTPUTS FOR IN-VITRO DIAGNOSTIC SUBSTANCE MANUFACTURING - Continued
Economic Sector or Industry Providing Inputs	%	Sector	Economic Sector or Industry Buying Outputs	%	Sector
Source: Benchmark Input-Output Accounts for the U.S. Economy, 2002, U.S. Department of Commerce, Washington, D.C., January 2008. The abbreviation nec stands for ‘not elsewhere classified’.
Architectural, engineering, & related services	0.2	Services
Automotive equipment rental & leasing	0.2	Fin/R.E.
Services to buildings & dwellings	0.2	Services
Employment services	0.2	Services
Maintenance/repair of nonresidential structures	0.2	Construct.
Environmental & other technical consulting services	0.2	Services
Other computer related services, including facilities	0.2	Services
Office administrative services	0.2	Services
Plastics bottles	0.2	Manufg.
Petroleum refineries	0.2	Manufg.
Plastics packaging materials, film & sheet	0.2	Manufg.
Animal, except poultry, processing	0.2	Manufg.
Fabricated metals, nec	0.1	Manufg.
Chemical products & preparations, nec	0.1	Manufg.
Securities, commodity contracts, investments	0.1	Fin/R.E.
Industrial gases	0.1	Manufg.
Automotive repair & maintenance, ex. car washes	0.1	Services
Pressed & blown glass & glassware, nec	0.1	Manufg.
Commercial & industrial machinery rental & leasing	0.1	Fin/R.E.
Nondepository credit intermediation activities	0.1	Fin/R.E.
Hotels & motels, including casino hotels	0.1	Services

OCCUPATIONS EMPLOYED BY PHARMACEUTICAL & MEDICINE MANUFACTURING
Occupation	% of Total 2006	Change to 2016	Occupation	% of Total 2006	Change to 2016
Source: Industry-Occupation Matrix, Bureau of Labor Statistics, December 4, 2007. These data are reported based on 4-digit NAICS categories but have been matched to corresponding 6-digit NAICS industry codes. The change reported for each occupation to the year 2016 is a percent of growth or decline as estimated by the Bureau of Labor Statistics. The abbreviation nec stands for ‘not elsewhere classified’.
Packaging & filling machine operators & tenders	7.0	13.4	General & operations managers	1.6	13.4
Chemists	5.2	13.4	Biochemists & biophysicists	1.4	26.0
Mixing & blending machine operators & tenders	3.6	26.0	Machine feeders & offbearers	1.4	13.4
Chemical equipment operators & tenders	3.5	26.0	Packers & packagers, hand	1.4	0.8
Medical scientists, exc epidemiologists	3.4	26.0	Shipping, receiving, & traffic clerks	1.4	21.3
Inspectors, testers, sorters, samplers, & weighers	3.0	18.8	Customer service representatives	1.4	38.6
First-line supervisors/managers of production workers	2.6	26.0	Secretaries, exc legal, medical, & executive	1.3	12.1
Biological technicians	2.5	26.0	Industrial production managers	1.3	26.0
Chemical technicians	2.3	26.0	Managers, nec	1.3	26.0
Maintenance & repair workers, general	2.1	26.0	Production workers, nec	1.2	23.7
Sales representatives, wholesale & manufacturing, tech	2.0	26.0	Office clerks, general	1.2	24.2
Separating, precipitating, & still machine operators	1.9	26.0	Microbiologists	1.1	26.0
Business operation specialists, nec	1.8	38.6	Industrial machinery mechanics	1.1	44.9
Executive secretaries & administrative assistants	1.7	26.0	Accountants & auditors	1.1	26.0
Team assemblers	1.7	26.0	Natural sciences managers	1.1	26.0
Laborers & freight, stock, & material movers, hand	1.6	13.4	Production, planning, & expediting clerks	1.1	26.0

INDUSTRY DATA BY STATE
State	Establishments	Shipments			Employment				Cost as % of Shipments	Investment per Employee($)
State	Establishments	Total ($ mil)	% of U.S.	Per Establ.	Total Number	% of U.S.	Per Establ.	Wages ($/hour)	Cost as % of Shipments	Investment per Employee($)
Source: 2002 Economic Census. The states are in descending order of shipments or establishments (if shipment data are missing for the majority). The symbol (D) appears when data are withheld to prevent disclosure of competitive information. States marked with (D) are sorted by number of establishments. A dash (-) indicates that the data element cannot be calculated. Data may not show all states active in the NAICS category. All data available at the time of publication are shown.
California	67	1,595.6	21.9	23,815.1	7,701	28.7	115	22.01	22.7	14,297
New York	9	573.6	7.9	63,733.3	1,774	6.6	197	24.00	19.9	13,541
Massachusetts	11	459.3	6.3	41,753.0	1,976	7.4	180	16.03	16.0	10,503
Texas	13	137.9	1.9	10,604.0	553	2.1	43	27.00	41.5	4,479
Minnesota	6	125.1	1.7	20,851.0	292	1.1	49	24.75	36.7	10,747
Maine	7	124.4	1.7	17,767.0	1,294	4.8	185	24.54	25.4	5,389
Florida	5	99.7	1.4	19,946.6	449	1.7	90	22.73	30.1	10,085
Wisconsin	7	45.1	0.6	6,445.4	231	0.9	33	16.43	23.5	4,545