Encyclopedias, Almanacs, Transcripts, and Maps
- speedwell
- Spelman College
- Spence, Michael
- Spencer Gulf
- Spencer, George John Spencer, 2d Earl
- Sperry, Roger Wolcott
- sphenodon
- sphere of influence
- Spice Islands
- spicebush
- spider-flower
- spiderhunter
- spiderwort
- Spieghel, Hendrick Laurenszoon
- Spielberg
- Spielhagen, Friedrich
- spin electronics
- spinal puncture
- Spinello di Luca Spinelli
- Spinola, Ambrogio