titration Method used in analytical chemistry to determine the concentration of a compound in a solution by measuring the amount needed to complete a reaction with another compound. A solution of known concentration is added in measured amounts to a liquid of unknown concentration until the reaction is complete. The volume added enables the unknown concentration to be calculated.

titration (ty-tray-shŏn) n. a method of determining the concentration of a substance in solution. A measured volume of a reagent of known concentration is added to a known volume of the test solution until the end point of the reaction has occurred.